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News

AllSci
allsci.com > news > clinical-trials > regn7041-uveitis-trial-regeneron-terminates-phase

Regeneron halts first-in-human REGN7041 trial after safety event

4+ hour, 21+ min ago   (113+ words) REGN7041 targets CD3, a component of the T-cell receptor complex, and was being developed as an immunomodulatory approach to non-infectious uveitis, a group of inflammatory eye diseases that can cause vision loss. Regeneron listed the candidate in Phase I development for uveitis…...

AllSci
allsci.com > news > first-in-human-trials > crispr-treg-therapy-cancer-coregens-crispr-edited

CoRegen takes CRISPR-edited Tregs into first human cancer trial

3+ hour, 7+ min ago   (143+ words) Most clinical-stage adoptive cell therapy strategies for solid tumors center on cytotoxic effector populations, including engineered CAR-T cells and tumor-infiltrating lymphocytes (TILs). CRG-150 instead uses gene-edited Tregs as the therapeutic cell population, and no other publicly disclosed clinical oncology program…...

Google News
genengnews.com > topics > bioprocessing > car-t-manufacturing-innovation-expands-patient-access

CAR T Manufacturing Innovation Expands Patient Access

6+ hour, 9+ min ago   (432+ words) By Mike May, PhD Credit: Image generated with Google Gemini Speaking to GEN, experts from VIVEbiotech, Terumo Blood and Cell Technologies, and Bracco describe an industry transitioning from demonstrating scientific feasibility to building robust manufacturing systems capable of delivering life-changing…...

Google News
genengnews.com > topics > bioprocessing > vector-production-a-bottleneck-for-gene-therapy-sector

Vector Production a Bottleneck for Gene Therapy Sector

6+ hour, 10+ min ago   (588+ words) By Gareth John Macdonald Inefficiencies that limit the global supply of viral vectors are negatively impacting the gene therapy industry, according to researchers, who say there is an urgent need for better downstream purification materials. The call came from Stefano…...

MarketScreener
marketscreener.com > news > maxcyte-launches-change-seq-bea-and-one-seq-bea-to-strengthen-off-target-assessment-for-genome-e-ce7859d2db89f224

MaxCyte launches CHANGE-seq-BE™ and ONE-seq-BE™ to strengthen off-target assessment for genome editing therapies

6+ hour, 5+ min ago   (341+ words) marketscreener.com 19, 2026 (GLOBE NEWSWIRE) -- MaxCyte, Inc (NASDAQ: MXCT), a leading, cell-engineering focused company providing enabling platform technologies to advance the discovery, development and commercialization of next-generation cell therapeutics, today announced the launch of the CHANGE-seq-BE™ and ONE-seq-BE™ off-target nomination assays…...

CRISPR Medicine
crisprmedicinenews.com > news > crispr-screens-map-interferon-regulation-in-monocytes

News: CRISPR screens map interferon regulation in monocytes

7+ hour, 51+ min ago   (176+ words) Genome-wide CRISPR-Cas9 screens identified hundreds of genes that support or restrict cGAS–STING-induced type I interferon expression in human monocytic cells. The resulting map links interferon regulation to autophagy, RNA metabolism, and chromatin modification, and implicates TBL1XR1 and HDAC3 in promoting TBK1-mediated…...

STAT
statnews.com > 08/19/2026 > huidagene-clinical-trial-deaths-experts-dissect-study-design

In wake of boy’s death, gene editing experts dissect Huidagene’s decisions

9+ hour, 35+ min ago   (136+ words) Three months before a young boy died in Huidagene’s gene editing trial last year, the company’s former CEO Alvin Luk presented its early data at the American Society for Gene and Cell Therapy’s Presidential Symposium, one of the field’s biggest…...

The Medicine Maker
themedicinemaker.com > issues > 2026 > articles > august > the-road-to-commercial-scale-ipsc-cell-therapy

The Road to Commercial-Scale iPSC Cell Therapy

9+ hour, 36+ min ago   (562+ words) Here, Stefan Braam, Chief Technical Officer at Cellistic, discusses the evolution of allogeneic cell therapy, the bottlenecks that still limit iPSC manufacturing, and what it will take to make these therapies scalable, reproducible, and accessible. How has the allogeneic cell…...

NC State University
cals.ncsu.edu > international-programs > news > epigenetics-research-japan

Epigenetics Research in Japan

1+ day, 12+ hour ago   (84+ words) NC State University I spent my summer in Nagoya, Japan, conducting research at Nagoya University in Dr. Kenji Ichiyanagi’s Laboratory of Genome and Epigenome Dynamics under the guidance of Torahiko Yamanaka. My research focused on the epigenetic regulation of meiotic…...

BioProcessOL
bioprocessonline.com > doc > what-goes-into-restarting-a-shelved-orphan-drug-candidate-0001

What Goes Into Restarting A Shelved Orphan Drug Candidate?

13+ hour, 26+ min ago   (1109+ words) Guest Column | August 19, 2026 A conversation between Elizabeth White of the Orphan Therapeutics Accelerator and Life Science Connect's Jon O'Connell No advanced therapy developer feels good about abandoning a clinical-phase orphan drug candidate that they know has a real chance at…...