9+ hour, 30+ min ago  (399+ words) Cats with dementia have brain changes similar to those of people with Alzheimer's disease, offering a valuable model for studying the condition in humans, a study says. Scientists discovered a build-up of the toxic protein amyloid-beta in the brains of…...

4+ hour, 39+ min ago  (545+ words) One simple screening tool for cognitive impairment is the clock-drawing test (CDT): the patient is provided with a printed circle and asked to draw a clock face with the hands pointing to a certain. .....

1+ week, 5+ day ago  (281+ words) Cognitive reserve is associated with delayed symptom onset and slower clinical progression among individuals with dominantly inherited Alzheimer disease (AD), according to a study published in Neurology. Cognitive reserve has been shown to influence symptom onset and disease progression in…...

3+ week, 2+ day ago  (508+ words) Alpha-synuclein is a small presynaptic protein that, under normal conditions, exists largely in a disordered conformation and participates in synaptic vesicle trafficking and neurotransmitter release. View the latest institution rankings View the latest Country/territory rankings Alpha-Synuclein Interactions in Neurodegenerative…...

3+ week, 2+ day ago  (113+ words) The graph below shows the total number of articles in alpha-synuclein dynamics in neurodegenerative disorders across all publications each year (not limited to Nature Index journals). Protofilament: A linear chain of protein subunits that associates laterally with other protofilaments to…...

3+ week, 2+ day ago  (127+ words) The graph below shows the total number of articles in protein misfolding dynamics in neurodegenerative disorders across all publications each year (not limited to Nature Index journals). Protein misfolding: Failure of a polypeptide to attain its native three-dimensional structure, leading…...

9+ hour, 30+ min ago  (376+ words) Now, a new study by UC San Francisco researchers has made a leap toward answering that question -- by combining brain imaging, genetics, and advanced mathematical modeling into a powerful new lens. The study, published July 9 in Brain, shows multiple distinct…...

4+ week, 1+ day ago  (120+ words) No recent Nature Portfolio content available. The graph below shows the total number of articles in caffeine effects on physical and cognitive performance across all publications each year (not limited to Nature Index journals). Adenosine receptor antagonism: blockade of adenosine…...

2+ hour, 14+ min ago  (208+ words) LAS VEGAS (FOX5) " The "Welcome to Fabulous Las Vegas" sign will glow purple Monday to raise awareness for Alzheimer's and brain health. Clark County Commissioner Justin Jones will host a ceremony at the sign on June 1 at 8 a. m. The iconic landmark will…...

1+ mon, 5+ day ago  (101+ words) Results consistent with pre-clinical studies demonstrating that, in the early stages of the neurodegenerative process, disease progression in the basal forebrain is reversible Findings also correlate with previously reported results on neflamapimod's observed effects on a blood biomarker of neurodegenerative…...